Essay on medical ethics in drug trials.
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How are drug trials used to compare drugs?
Introduction In most therapeutic areas, multiple drug options are increasingly becoming available, but there is often a lack of evidence from head-to-head clinical trials that allows for direct comparison of the efficacy (and/or safety) of one drug vs.another.
Why are indirect analyses used in drug trials?
MTCs reduce uncertainty but have not yet been widely accepted by researchers, nor drug regulatory and reimbursement authorities. All indirect analyses are based on the same underlying assumption as meta-analyses, namely that the study populations in the trials being compared are similar.
How are statistical methods used in clinical trials?
In the absence of head-to-head clinical trial data, several statistical methods have been developed over the past 15 years to allow for indirect comparison between or among various drugs (or other interventions).
What was the purpose of the monkey drug trials experiment?
Monkey Drug Trials Experiment. Title: Monkey Drug Trials Experiment Authors: Deneau, Yanagita & Seevers Year: it was done in 1969 Purpose: The purpose of the experiment was to look at the effects of self-administration on drugs, drug abuse, and drug dependence in humans, by testing it on monkeys.
Last Update: Oct 2021
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